The Extension Opioid Crisis Response Workgroup (EOCRW) was given a charge from the Extension Committee on Organization and Policy (ECOP) to identify and assemble resources to help Extension play a stronger and more strategic role in addressing the opioid crisis, and more generally behavioral health challenges that emerge over time. This publication provides useful information to help the Land Grant Extension system play a larger role in helping to address the crisis. This resource provides information about: the findings of a nationwide survey of Extension Behavioral Health programming; an extensive literature review on opioids and substance abuse; links to potential partners, networks, and grant opportunities; and the Extension Opioid Response Strategic Plan Report.